… study was aimed to compare the effectiveness and safety of erlotinib and gefitinib in
NSCLC patients… The use of EGFR inhibitors can cause some adverse drug reactions (ADRs) …

… adverse events for afatinib, gefitinib, and erlotinib were approximately 7%, 3%, and 2%,
respectively, in our study, … efficacy in another retrospective study [19]. It showed that there was no …

… -related adverse event and fatal adverse event in afatinib group compared to gefitinib group
(11… Moreover, other similar retrospective study performed by Krawcyzk et al. [11] showed that …

… Totally, adverse events regardless … study was designed as a retrospective analysis and
some bias could not be avoided, and the patient management was not sufficient when compared …

… of CNS failure compared with gefitinib or erlotinib. However, our study, as a retrospective
study, has significant limitation for the accurate comparison of CNS efficacy, so cautious …

… effectiveness compared to gefitinib after performing a multivariate Cox regression analysis.
… with better ECOG PS to avoid higher grade (grade ¾) adverse events after afatinib treatment…

… /interruption), drug discontinuation, tumor response, adverse events (AEs), and subsequent
… for older patients compared to erlotinib or gefitinib. The characteristics of younger and older …

… proportion of early stage non-small cell lung cancer (NSCLC) … a retrospective study to compare
the clinical efficacy among … had a similar detrimental effect in patients with stage IA stage …

… Retrospective studies also supported this notion … difference was observed in the incidence
of adverse events of any grade or adverse events of grade 3–4 between erlotinib and gefitinib. …

… We compared the effects of erlotinib+bevacizumab … and severity of adverse events. We
also conducted subgroup … explore the efficacy and adverse events of erlotinib+bevacizumab …